- Our new paper in European Journal of Cell Biology summarizes important discoveries in Batten disease research using Dictyostelium discoideum as a model system. It is also Adam's first publication. Congratulations Adam! See Publications page for more details.
- Our new paper in Frontiers in Genetics examines the effect of cln5 gene deletion on the transcriptome in Dictyostelium discoideum. See Publications page for more details.
- The Huber Lab welcomes Cassandra and Adam who will be completing undergraduate Honour's theses in the lab.
- Will is currently at Harvard Medical School and Massachusetts General Hospital completing an internship in Dr. Susan Cotman's lab. You can read about Will's exciting experience here: https://www.trentu.ca/news/story/34087
- Will presented his work at the 2022 International Dictyostelium Conference in Scotland.
- Awesome new YouTube video describing the Dictyostelium life cycle: https://www.youtube.com/watch?v=vlANF-v9lb0
- Congrats to Elicia on publishing her MSc thesis in Frontiers in Cell and Developmental Biology. See Publications page for more details.
- Congrats to Will on securing a 3-year Canada Graduate Scholarship from NSERC!
- New papers this month in BMC Neuroscience, Frontiers in Physiology, and Frontiers in Cell and Developmental Biology. See Publications page for more details.
- Our 2019 paper in Biomolecules has been awarded the Biomolecules 2021 Best Video Abstract Award!
- Congratulations Elicia on successfully defending your MSc thesis!
- Check out our new review in Disease Models & Mechanisms that discusses the role of altered protein secretion in Batten disease. See Publications page for more details.
- Check out the Trent News story about Megan's International Dicty Award!
- We welcome new graduate students Joshua Gray and Adam Remtulla and new undergrad Thomas Burnside into the lab!
- Congrats to Megan on being awarded the 2021 International Dictyostelium Graduate Student Award. A well deserved accomplishment!
- A total team effort from the Huber Lab! Check out our new paper in Frontiers in Cell and Developmental Biology entitled "Aberrant autophagy impacts growth and multicellular development in a Dictyostelium knockout model of CLN5 disease". See Publications page for more details.
- Congratulations to Elicia on being awarded a 2021 David and Joyce Woods Graduate Scholarship!
- Check out our new paper in Biomolecules that examines the effect of Pevonedistat (MLN4924) on Dictyostelium growth and development. Pevonedistat is currently being explored as a potential therapy for cancer, chronic liver diseases, and autoimmune diseases. See Publications page for more details.
- Our article "The converging roles of Batten disease proteins in neurodegeneration and cancer" has been accepted for publication in iScience. See Publications page for more details.
- Our paper that provides a catalogue of calmodulin-binding proteins in Dictyostelium has been accepted for publication by International Journal of Molecular Sciences and will appear in the Special Issue: Calmodulin Binding Proteins. See Publications page for more details.
- Congrats to Will on a successful conversion to the Ph.D. program!
- Check out our new paper in BioEssays that describes how Dictyostelium can be used to gain insight into the pathways that regulate the breakdown of multicellularity in cancer. This is an exciting paper that was the result of a collaboration with the Dellaire Lab at Dalhousie University. See Publications page for more details.
- Kaitlyn Neuman, a Huber Lab alumnus, was recently featured in the Huntington Society of Canada's Newsletter "Horizon" (Issue 162 - Fall). Congratulations Kaitlyn! https://www.huntingtonsociety.ca/horizon/
- Rob is serving as a Guest Associate Editor for a Research Topic in Frontiers in Cell and Developmental Biology. Click the link for more information: https://www.frontiersin.org/research-topics/16964/dictyostelium-a-tractable-cell-and-developmental-model-in-biomedical-research
- Megan's 2019 paper in Biomolecules was recently recognized as an "Editor's Choice Article" by the Editors of the Journal: https://www.mdpi.com/2218-273X/9/11/702. Congratulations Megan!
- YouTube link: https://www.youtube.com/watch?v=sI6gYDWqxSU&feature=youtu.be
- Rob is serving as a Guest Editor for a Special Issue on Calmodulin Binding Proteins in the International Journal of Molecular Sciences. Click the link below for more details. Submission closes January 31, 2021.https://www.mdpi.com/journal/ijms/special_issues/Calmodulin_Proteins
- Check out Megan's new paper in Frontiers in Cell and Developmental Biology that details the functions of cytokinins during the Dictyostelium life cycle. See Publications page for more details.
- Congrats to Elicia and Will on securing Ontario Graduate Scholarships for 2020-2021. Also, congrats to Megan for receiving a highly prestigious NSERC CGS D. Well done everyone!
- Congratulations to Meagan on successfully defending her M.Sc. thesis!
- Rob's new paper entitled "Molecular networking in the neuronal ceroid lipofuscinoses: Insights from mammalian models and the social amoeba Dictyostelium discoideum" has been accepted for publication in Journal of Biomedical Science. See Publications page for more details.
- Rob is excited to announce that the encyclopedia of using cellular models to study Batten disease has been accepted for publication in BBA Molecular Basis of Disease. See Publications page for more details.
- Congratulations Megan on your recently accepted paper in Biomolecules.
- The Huber lab is currently recruiting graduate students and a postdoc for January 2020. Interested applicants should email Dr. Huber directly (firstname.lastname@example.org) with an updated CV, transcript, and statement of interest.
- Congratulations to Rob on winning the 2019 Dictyostelium Junior Faculty Award, which was presented at the 2019 International Dictyostelium Conference!
- Meagan, Megan, Elicia and Rob presented their work at the 2019 International Dictyostelium meeting.
- The Huber lab is excited to announce that our application to the CIHR Project Grant competition was approved for 5 years of funding! We will post new graduate student and postdoc positions sometime in the near future.
- The Huber lab is excited to join the Molecules, Cells & Systems Research Group at Trent University. You can read more about this new initiative here: https://www.trentu.ca/researchinnovation/trent-research-matters/centres-and-institutes
- We are happy to welcome Evan Schuett into the lab as a graduate student.
- Congratulations to Will and Ali on receiving NSERC USRAs.
- Congratulations to Elicia on receiving the Zobel Conference Travel Award. Elicia will be presenting her exciting work on Mfsd8 function in Dictyostelium at the Dicty 2019 meeting!
- Congratulations to Will on receiving an NSERC CGS M! Will will be starting his M.Sc. in the Huber lab in September.
- Check out our new paper in Cellular Signalling that explores the mechanisms underlying Cln3 function in Dictyostelium. See Publications page for details.
- Read our latest paper to learn how Dictyostelium is being used to study the functions of proteins linked to Batten disease. See Publications page for more details.
- Check out our new paper that sheds light on the potential involvement of calmodulin in Batten disease. See Publications page for more details.
- Congratulations to Elicia and Will on receiving their 2018 Chemistry Awards!
- Congrats to Meagan on receiving a travel award from the International Society for Neurochemistry to attend the NCL 2018 meeting in London, UK!
- Our paper entitled "Cln3 function is linked to osmoregulation in a Dictyostelium model of Batten disease" has been accepted for publication in BBA Molecular Basis of Disease! See Publications page for more details.
- Trent University News wrote a nice story about our recent funding from the Banting Research Foundation www.trentu.ca/news/story/21869
- Hot off the press! Our new paper entitled "Secretion and function of Cln5 during the early stages of Dictyostelium development" has been accepted for publication in BBA Molecular Cell Research. See Publications page for more details.
- We are excited to welcome Elicia Yap and William Kim into the lab. Elicia and William will be working on their Biochemistry and Molecular Biology research theses during the 2018-2019 academic year.
- We received some great news today. Our grant entitled "Using the social amoeba Dictyostelium discoideum to study neuronal ceroid lipofuscinosis" has been funded by the Banting Research Foundation. We would like to thank the Foundation for their generous support of our work.
- Congratulations to Saby on placing 2nd in Trent University's 4th Annual Three Minute Paper (3MP) Competition. Saby did a great job describing how we use Dictyostelium to study Batten disease. You can read about the competition here: http://www.trentu.ca/newsevents/newsDetail.php?newsId=20
- Congratulations to Saby on being awarded an NSERC Undergraduate Student Research Award for Summer 2018
- Trent University News wrote a nice story on our recent paper. Check it out here: http://www.trentu.ca/newsevents/newsDetail.php?newsId=19807
- Our paper on Cln5 localization and function in Dictyostelium has been accepted for publication in Cellular Signalling. See Publications page for more details.
- We are excited to welcome Meagan McLaren into the lab as a M.Sc. student!
- Check out our recent paper entitled "Dictyostelium discoideum: A model system for cell and developmental biology" which will appear in Current Protocols Essential Laboratory Techniques. See Publications page for more details.
- To learn more about how we can use Dictyostelium to study neurodegeneration, check out our recent book chapter entitled "Functional Analysis of Proteins Involved in Neurodegeneration Using the Model Organism Dictyostelium: Alzheimer’s, Huntington’s and Batten Disease" which will appear in the Second Edition of Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research. See Publications page for more details.
- Rob and Saby had a great time at the Canadian Society for Molecular Biosciences Annual Meeting where they presented their work on using Dictyostelium as a model system for studying NCL.
- Our paper entitled "Loss of Cln3 impacts protein secretion in the social amoeba Dictyostelium" has been accepted for publication in Cellular Signalling. See Publications page for more details.
- We would like to acknowledge the generous support provided by the Canada Foundation for Innovation through the John R. Evans Leaders Fund. See Media page for more details.
- Congratulations to Saby on being awarded an NSERC Undergraduate Student Research Award for Summer 2017
- Check out our recently published papers in Cell Adhesion & Migration, Biochimica et Biophysica Acta, and Journal of Biomedical Science. See Publications page for more details.
- Profile on Dr. Huber's research program at Trent University: https://www.trentu.ca/newsevents/newsDetail.php?newsId=16991